Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Trp63  transformation related protein 63   (Synonyms: deltaNp63, KET protein, p51/p63, p63, p73L, TAp63, Trp53rp1)
Results	Reference
1	J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801
1	J:218613 Chen J, Laclef C, Moncayo A, Snedecor ER, Yang N, Li L, Takemaru K, Paus R, Schneider-Maunoury S, Clark RA, The ciliopathy gene rpgrip1l is essential for hair follicle development. J Invest Dermatol. 2015 Mar;135(3):701-9
1	J:177389 Chikh A, Matin RN, Senatore V, Hufbauer M, Lavery D, Raimondi C, Ostano P, Mello-Grand M, Ghimenti C, Bahta A, Khalaf S, Akgul B, Braun KM, Chiorino G, Philpott MP, Harwood CA, Bergamaschi D, iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia. EMBO J. 2011;30(20):4261-73
1	J:95347 Daniely Y, Liao G, Dixon D, Linnoila RI, Lori A, Randell SH, Oren M, Jetten AM, Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am J Physiol Cell Physiol. 2004 Jul;287(1):C171-81
1	J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767
1	J:181779 Driskell I, Oda H, Blanco S, Nascimento E, Humphreys P, Frye M, The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin. EMBO J. 2012 Feb 1;31(3):616-29
1	J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543
1	J:193630 Fujimoto A, Kurban M, Nakamura M, Farooq M, Fujikawa H, Kibbi AG, Ito M, Dahdah M, Matta M, Diab H, Shimomura Y, GJB6, of which mutations underlie Clouston syndrome, is a potential direct target gene of p63. J Dermatol Sci. 2013 Feb;69(2):159-66
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:268534 He Y, Hooker E, Yu EJ, Wu H, Cunha GR, Sun Z, An Indispensable Role of Androgen Receptor in Wnt Responsive Cells During Prostate Development, Maturation, and Regeneration. Stem Cells. 2018 Jun;36(6):891-902
1	J:315539 Hu L, Liu J, Li Z, Ozturk F, Gurumurthy C, Romano RA, Sinha S, Nawshad A, TGFbeta3 regulates periderm removal through DeltaNp63 in the developing palate. J Cell Physiol. 2015 Jun;230(6):1212-25
1	J:194043 Iwata J, Suzuki A, Pelikan RC, Ho TV, Sanchez-Lara PA, Urata M, Dixon MJ, Chai Y, Smad4-Irf6 genetic interaction and TGFbeta-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. Development. 2013 Mar;140(6):1220-30
1	J:266277 Joseph DB, Chandrashekar AS, Abler LL, Chu LF, Thomson JA, Mendelsohn C, Vezina CM, In vivo replacement of damaged bladder urothelium by Wolffian duct epithelial cells. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8394-8399
1	J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9
1	J:244349 Kousa YA, Moussa D, Schutte BC, IRF6 expression in basal epithelium partially rescues Irf6 knockout mice. Dev Dyn. 2017 Sep;246(9):670-681
1	J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522
1*	J:171626 Li S, Xiang M, Foxn4 influences alveologenesis during lung development. Dev Dyn. 2011 Jun;240(6):1512-7
1	J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82
1	J:342615 Malin J, Martinez-Ruiz GU, Zhao Y, Shissler SC, Cowan JE, Ding Y, Morales-Sanchez A, Ishikawa M, Lavaert M, Das A, Butcher D, Warner AC, Kallarakal M, Chen J, Kedei N, Kelly M, Brinster LR, Allman D, Bhandoola A, Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development. Sci Adv. 2023 Nov 17;9(46):eadg8126
1	J:243772 Mamo TM, Wittern AB, Kleppa MJ, Bohnenpoll T, Weiss AC, Kispert A, BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017 Sep 15;26(18):3553-3563
1	J:291294 McAuley E, Moline D, VanOpstall C, Lamperis S, Brown R, Vander Griend DJ, Sox2 Expression Marks Castration-Resistant Progenitor Cells in the Adult Murine Prostate. Stem Cells. 2019 May;37(5):690-700
1*	J:316269 Mehta V, Schmitz CT, Keil KP, Joshi PS, Abler LL, Lin TM, Taketo MM, Sun X, Vezina CM, Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning. Dev Biol. 2013 Apr 15;376(2):125-35
1	J:257406 Metwalli KA, Do MA, Nguyen K, Mallick S, Kin K, Farokhnia N, Jun G, Fakhouri WD, Interferon Regulatory Factor 6 Is Necessary for Salivary Glands and Pancreas Development. J Dent Res. 2018 Feb;97(2):226-236
1	J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021
1	J:238903 Mori M, Mahoney JE, Stupnikov MR, Paez-Cortez JR, Szymaniak AD, Varelas X, Herrick DB, Schwob J, Zhang H, Cardoso WV, Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors. Development. 2015 Jan 15;142(2):258-67
1	J:135158 Moriyama M, Durham AD, Moriyama H, Hasegawa K, Nishikawa S, Radtke F, Osawa M, Multiple roles of Notch signaling in the regulation of epidermal development. Dev Cell. 2008 Apr;14(4):594-604
1*	J:85888 Nakamuta N, Kobayashi S, Expression of p63 in the testis of mouse embryos. J Vet Med Sci. 2003 Aug;65(8):853-6
1	J:226218 Peyrard-Janvid M, Leslie EJ, Kousa YA, Smith TL, Dunnwald M, Magnusson M, Lentz BA, Unneberg P, Fransson I, Koillinen HK, Rautio J, Pegelow M, Karsten A, Basel-Vanagaite L, Gordon W, Andersen B, Svensson T, Murray JC, Cornell RA, Kere J, Schutte BC, Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development. Am J Hum Genet. 2014 Jan 2;94(1):23-32
1*	J:197339 Pignon JC, Grisanzio C, Geng Y, Song J, Shivdasani RA, Signoretti S, p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8105-10
1*	J:326663 Qasrawi F, Meuser M, Lehnhoff F, Schulte M, Kispert A, S100A1 expression characterizes terminally differentiated superficial cells in the urothelium of the murine bladder and ureter. Histochem Cell Biol. 2022 Jun 1;
1	J:149564 Que J, Luo X, Schwartz RJ, Hogan BL, Multiple roles for Sox2 in the developing and adult mouse trachea. Development. 2009 Jun;136(11):1899-907
1	J:122531 Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan BL, Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development. 2007 Jul;134(13):2521-31
1	J:166768 Rodriguez P, Da Silva S, Oxburgh L, Wang F, Hogan BL, Que J, BMP signaling in the development of the mouse esophagus and forestomach. Development. 2010 Dec;137(24):4171-6
1	J:104733 Rufini A, Weil M, McKeon F, Barlattani A, Melino G, Candi E, p63 protein is essential for the embryonic development of vibrissae and teeth. Biochem Biophys Res Commun. 2006 Feb 17;340(3):737-41
1	J:170365 Sanchis A, Bayo P, Sevilla LM, Perez P, Glucocorticoid receptor antagonizes EGFR function to regulate eyelid development. Int J Dev Biol. 2010;54(10):1473-80
1	J:319645 Stefanski HE, Xing Y, Nicholls J, Jonart L, Goren E, Taylor PA, Mills AA, Riddle M, McGrath J, Tolar J, Hollander GA, Blazar BR, P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss. PLoS One. 2022;17(1):e0261770
1*	J:294646 Stupnikov MR, Yang Y, Mori M, Lu J, Cardoso WV, Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
1	J:238904 Suzuki D, Sahu R, Leu NA, Senoo M, The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells. Development. 2015 Jan 15;142(2):282-90
1	J:325729 Teng T, Teng CS, Kaartinen V, Bush JO, A unique form of collective epithelial migration is crucial for tissue fusion in the secondary palate and can overcome loss of epithelial apoptosis. Development. 2022 May 15;149(10):dev200181
1	J:139045 Thomason HA, Dixon MJ, Dixon J, Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling. Dev Biol. 2008 Sep 1;321(1):273-82
1	J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26
1	J:93433 Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ, The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc Natl Acad Sci U S A. 2004 Oct 28;101(39):14114-9
1	J:169856 Xin Y, Lu Q, Li Q, IKK1 Control of Epidermal Differentiation Is Modulated by Notch Signaling. Am J Pathol. 2011 Apr;178(4):1568-77
1	J:267640 Yang Y, Riccio P, Schotsaert M, Mori M, Lu J, Lee DK, Garcia-Sastre A, Xu J, Cardoso WV, Spatial-Temporal Lineage Restrictions of Embryonic p63(+) Progenitors Establish Distinct Stem Cell Pools in Adult Airways. Dev Cell. 2018 Mar 26;44(6):752-761.e4
1	J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687
1	J:243660 Zhu XJ, Yuan X, Wang M, Fang Y, Liu Y, Zhang X, Yang X, Li Y, Li J, Li F, Dai ZM, Qiu M, Zhang Z, Zhang Z, A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development. J Biol Chem. 2017 Jun 02;292(22):9409-9419